Enamel Matrix Derivative Stimulates Osteogenesis- and Chondrogenesis-related Transcription Factors in C3H10T1/2 Cells
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چکیده
منابع مشابه
Enamel matrix derivative stimulates human gingival fibroblast proliferation via ERK.
Emdogain, a formulation of Enamel Matrix Proteins, is used clinically for periodontal regeneration to stimulate PDL (periodontal ligament), cementum, and bone formation. Its effects on gingival fibroblasts and tissue have not been thoroughly studied. Therefore, we investigated the mechanisms by which Emdogain affects the cell cycle of human gingival fibroblasts. Without serum, Emdogain (50 micr...
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It has been shown that Emdogain Gel (Emd-Gel) containing enamel matrix proteins promotes biomineralization, such as osteogenesis and cementogenesis, during the regeneration of periodontal tissues. However, the growth factors involved in these activities of Emd-Gel remain unclear. In this study, Emd-Gel was fractionated into 22 sub-fractions by size exclusion chromatography. The osteoinductive f...
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statement of problem: it is not known whether endochondral and intramembranous bones have distinct biological characteristics. octacalcium phosphate (ocp), a hydroxyapatite precursor, has been reported to stimulate bone formation after being implanted in parietal bone defects of rats. purpose: the present study was designed to investigate the response of endochondral and intramembranous bones t...
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Various periodontal plastic surgical techniques are employed in obtaining root coverage. Recently, the use of an enamel matrix derivative (EMD) has been reported in such treatment. We report 2 cases of root coverage surgery with a coronally positioned flap in combination with EMD (CPF+EMD) and connective tissue graft in combination with EMD (CTG+EMD). Case 1: The patient was a 25-year-old woman...
متن کاملThe Use of Enamel Matrix Derivative
Background—Periodontal disease results in the loss of the attachment apparatus. In the last three decades, an increasing effort has been placed on seeking procedures and materials to promote the regeneration of this tissue. The aim of this paper is to evaluate the effect of enamel matrix derivative (EMD) during regenerative procedures. In addition, a meta-analysis is presented regarding the cli...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2007
ISSN: 1672-9145,1745-7270
DOI: 10.1111/j.1745-7270.2007.00250.x